Radom Ghetto was a World War II ghetto set up by Nazi Germany in the city of Radom during the occupation of Poland, for the purpose of the persecution and exploitation of Polish Jews. It was closed off from the outside officially in April 1941.

The liquidation of the ghetto began a year and a half later, in August of 1942. It ended in July of 1944, with approximately 30,000 to 32,000 victims (men, women, and children) deported by train to their deaths at the Treblinka extermination camp.